Oriheal Paladox-LB Doxycycline & Lactic Acid Bacillus Tablets for Dogs & Cats | 100mg, 200mg & 300mg

PRESCRIPTION VETERINARY MEDICINE — For veterinary use only. Must be prescribed and dispensed by or under the supervision of a licensed veterinarian. Complete the full prescribed course to prevent antimicrobial resistance and treatment failure. Do not use in pregnant animals — Doxycycline is a tetracycline-class antibiotic that can cause fetal skeletal abnormalities and tooth discolouration in developing young. Do not use in animals under 6 months of age due to risk of permanent tooth and bone discolouration. Administer with food or water to reduce risk of oesophageal ulceration. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

If you are giving this to a cat, always follow the tablet with water or food. A doxycycline tablet that lodges in a cat's oesophagus can burn through the lining and cause a stricture, a narrowing that permanently affects swallowing and is far harder to treat than the original infection. Give the tablet, then follow it immediately with about 5ml of water from a syringe or a small amount of wet food, and do not let your cat settle down straight afterwards. Tablet size matters here too: the smallest strength in this range is 100mg, which is more than a typical cat or small dog needs, so ask your veterinarian whether this presentation can be divided safely for your pet or whether a smaller strength is required. Never give leftover antibiotics from another animal or a previous illness, and never give human antibiotics to a pet. Contact your veterinarian if your pet gags, drools, repeatedly swallows, goes off food, vomits persistently, or develops severe diarrhoea during treatment.

Oriheal Paladox-LB Tablets for Dogs & Cats (100mg | 200mg | 300mg)

Oriheal Paladox-LB is a prescription veterinary combination antibiotic tablet for dogs and cats, containing Doxycycline (a second-generation tetracycline-class broad-spectrum bacteriostatic antibiotic) combined with Lactic Acid Bacillus (a veterinary probiotic). The dual-action formulation combines the broad-spectrum antibacterial activity of Doxycycline with the gut flora-protective activity of Lactic Acid Bacillus, reducing antibiotic-associated gastrointestinal disturbance during treatment. That pairing matters in Indian practice, because doxycycline's most common use here is tick fever, which is treated for around four weeks — long enough for gut flora disruption to become a real problem in its own right. Available in 100mg, 200mg, and 300mg tablet strengths for weight-based dosing. Administer strictly as directed by a licensed veterinarian.

Composition

• Doxycycline Hyclate or Monohydrate — 100mg, 200mg, or 300mg per tablet (confirm salt form from Oriheal Paladox-LB product label): Second-generation tetracycline-class broad-spectrum bacteriostatic antibiotic; mechanism of action — reversibly binds to the 30S ribosomal subunit of susceptible bacteria, blocking aminoacyl-tRNA binding to the mRNA-ribosome complex and thereby inhibiting bacterial protein synthesis; bacteriostatic activity (inhibits bacterial growth and replication, relying on host immune clearance to eliminate bacteria); spectrum — active against a broad range of Gram-positive and Gram-negative bacteria, atypical organisms (Mycoplasma, Chlamydia, Rickettsia), spirochaetes (Borrelia burgdorferi/Lyme disease), and intracellular obligate pathogens (Ehrlichia canis, Anaplasma phagocytophilum); superior tissue penetration compared to first-generation tetracyclines; longer half-life allowing once or twice daily dosing; Doxycycline monohydrate formulations cause less oesophageal irritation than hyclate formulations in cats (confirm salt form from label)
• Lactic Acid Bacillus (Lactobacillus sporogenes) — confirm CFU per tablet from product label: Spore-forming probiotic bacterium; produces lactic acid in the GI tract, creating an acidic intestinal environment that inhibits the growth of pathogenic bacteria and supports the re-establishment of normal commensal gut flora disrupted by Doxycycline therapy; reduces antibiotic-associated diarrhoea, GI dysbiosis, and digestive disturbance during antibiotic treatment courses
• Tablet excipients — confirm from Oriheal Paladox-LB product label

Therapeutic Class

• Prescription veterinary tetracycline-class broad-spectrum antibiotic with probiotic combination tablet for dogs and cats — bacterial infections, tick-borne disease, respiratory, urinary tract, skin, and gastrointestinal infection treatment

Indications

• Tick-borne diseases — Ehrlichia canis (canine ehrlichiosis/tick fever), Anaplasma phagocytophilum (anaplasmosis), Rickettsia spp., Borrelia burgdorferi (Lyme disease); Doxycycline is the veterinary drug of choice for these intracellular tick-borne bacterial pathogens
• Respiratory tract infections — bacterial pneumonia, tracheobronchitis (kennel cough), Mycoplasma pneumonia, Bordetella bronchiseptica (in combination), and other Doxycycline-susceptible respiratory pathogens
• Urinary tract infections — bacterial cystitis and UTIs caused by Doxycycline-susceptible organisms
• Skin and soft tissue infections — pyoderma, wound infections, cellulitis, and other bacterial skin infections caused by susceptible organisms
• Gastrointestinal infections caused by Doxycycline-susceptible organisms
• Brucellosis (Brucella canis) — adjunctive therapy in a combination protocol as directed by your veterinarian
• Leptospirosis — treatment and prophylaxis in dogs (confirm protocol with your veterinarian)
• Gut flora maintenance during antibiotic therapy — the Lactic Acid Bacillus component supports the intestinal microbiome and reduces antibiotic-associated GI effects

Dosage

• Administer strictly as directed by a licensed veterinarian — this is a prescription veterinary medicine
• Standard veterinary dosing: Doxycycline 5–10mg/kg once daily or 2.5–5mg/kg twice daily orally; tick-borne disease (Ehrlichia canis) typically treated at 10mg/kg once daily for 28 days — confirm indication-specific dose, dosing interval, and treatment duration from the product label or veterinary prescription
• The 100mg tablet is suitable for small to medium dogs; 200mg for medium dogs; 300mg for large breed dogs — confirm weight-based strength selection with your veterinarian, particularly for cats and very small dogs
• Administer orally with food or water; do not allow the animal to lie down immediately after administration — follow every dose with water or a small amount of food to ensure the tablet reaches the stomach
• Give at evenly spaced intervals to maintain steady blood levels
• Complete the full prescribed course even if clinical improvement is observed early — stopping antibiotic therapy early risks treatment failure and antimicrobial resistance

Contraindications

• Do not use in pregnant animals — Doxycycline crosses the placenta and can cause fetal skeletal abnormalities, retarded bone growth, and permanent tooth discolouration in developing young
• Do not use in lactating animals — Doxycycline is excreted in milk and can affect nursing young
• Do not use in animals under 6 months of age — Doxycycline binds to calcium in developing teeth and bones, causing permanent yellow-grey tooth discolouration and potential bone growth effects
• Do not use in animals with known hypersensitivity to Doxycycline, other tetracyclines, or any tablet excipient
• Use with caution in animals with hepatic disease — Doxycycline is metabolised and excreted via the biliary system
• Use with caution in animals with oesophageal disorders or swallowing difficulties — increased oesophageal ulceration risk

Drug Interactions

• Antacids, dairy products, iron supplements, calcium, magnesium, aluminium salts: Chelate Doxycycline in the GI tract, significantly reducing oral absorption; administer at least 2 hours before or after antacid or mineral supplement administration — this includes giving it with milk or a calcium-rich treat
• Barbiturates (phenobarbital), rifampicin: Hepatic enzyme inducers — increase Doxycycline metabolism and reduce plasma levels; may require dose adjustment
• Penicillin-class antibiotics (amoxicillin, ampicillin): Bacteriostatic antibiotics can antagonise bactericidal antibiotics — avoid concurrent use unless specifically directed by your veterinarian
• Anticoagulants (warfarin): Doxycycline may potentiate anticoagulant effect; monitor coagulation if concurrent use is necessary
• Ciclosporin: Minor interaction; monitor for increased GI side effects

Safety Information

• Prescription veterinary medicine — must be prescribed and dispensed by or under the supervision of a licensed veterinarian
• Oesophageal ulceration risk: always administer with food or water, particularly in cats — oesophageal stricture from Doxycycline-induced ulceration is a well-documented serious adverse effect in cats; follow each dose with a 5ml water bolus or food
• Photosensitivity: Doxycycline can cause photosensitisation in some animals — limit sun exposure during treatment
• Hepatotoxicity: rare but possible with prolonged use — monitor liver enzymes (ALT, ALP) on extended courses
• Antimicrobial resistance: complete the full prescribed course; do not use leftover antibiotics without veterinary guidance; culture and sensitivity testing is recommended where possible
• Tick prevention remains essential — treating tick fever does not stop reinfection, so maintain an effective tick control product
• Not for human use — keep out of reach of children
• Store in a cool, dry place away from direct sunlight and moisture; protect from light; keep in original packaging